ncRNA name | survivin siRNA |
ncRNA Category | siRNA |
Disease name | pterygium |
Species | Homo sapiens |
Tissues/Cell_line | pterygium epithelial cells (PEC) |
Methods | siRNA transfection, qRT-PCR, immunostaining, Western blot, CCK-8 assay |
Expression pattern | associated |
Functional description | Survivin was highly expressed in all pterygium tissues. The knockdown of survivin by siRNA inhibited proliferation of PECs, accompanied by downregulation of p63, and upregulation of p57 and p21. |
PubMed ID | 25468890 |
Year | 2014 |
Title | Differential expression and function of survivin during the progress of pterygium. |
Drug-related ncRNA | NO |
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